Organic Chemistry

- To know the most important functional groups present in the organic compounds. To understand and to be able of using the IUPAC nomenclature system.
- To be able to represent organic compounds using Lewis's structures, structural formulae and with stereochemistry (Newmanm, Fischer, perspective) and using computer applications.
- To have basic notions of stereochemistry and conformational analysis.
- To relate physical properties (melting points, boiling points, solubility in water) with molecular structure.
- To know the main methods of separation of organic substances and their practical implementation.
- To know the most relevant chemical reactions of the functional groups studied.
- To know the industrial and environmental importance of organic compounds
- To develop oral communication skills.

TOPIC 1: STRUCTURE AND NOMENCLATURA OF ORGANIC COMPOUNDS
Representation of organic molecules. Structural isomerism. Functional groups. Resonance. Hiybridization. Polarity. Intermolecular forces. Acids and bases.

TOPIC 2: ALKANES.
Physical properties. Conformacional analysis of Alkanes and cycloalkanes. Combustion. Halogenation. Petroleum.

TOPIC 3: STEREOCHEMISTRY. Chirality. Optical activity. Absolute configuration. Fischer Projection. Stereoisomerism.

TOPIC 4: ALKENES and ALKYNES
Alkenes: Structure and industrial importance. Electrophilic Aaddition to alkenes. Oxidation. Reduction. Diels-Alder's reaction. Polimerization.
Alkynes: structure. Acidity of alkynes. Reactivity of alkynes.

TOPIC 5: AROMATIC COMPOUNDS:
Structure of benzene and aromaticity. Electrophilic aromatic substitution. Aromatic compounds: industrial importance.

TOPIC 6: HALOALKANES
Classification and importance. Nucleophilic substitution: SN1 and SN2 . Elimination: E1 and E2 .Organometallic compounds.

TOPIC 7: ALCOHOLS AND AMINES
Alcohols: classification and importance. Acid-base properties. Nucleophilic substitution with alcohols. Reactions of Alcohols with acids. Oxidation. Ethers and epoxides.
Amines: Classification and importance. Acidity and basicity of amines. Alkylation of amines and Quaternary ammonium salts.

TOPIC 8 ALDEHYDES AND KETONES
Structure and properties. Additions to the carbonyl group. Hemiacetals, acetals, imines, enamines. Alpha reactivity: aldol condensation. Oxidation and reduction. Carbohydrates.

TOPIC 9: CARBOXILIC ACIDS AND DERIVATIVES
Addition-elimination reactions. Transformation of carboxilic acids to their derivatives and interconversion of carboxilic acid derivatives.

LABORATORY:
SESSION 1: separation techniques:
a) Liquid-liquid extraction.
b) Column chromatography.
SESSION 2: Fisher esterification: ethyl acetate preparation.
SESSION 3: Preparation of polymers.

COMPUTER SESSION: use of computer applications to represent organic molecules.

BASIC BIBLIOGRAPHY

All the basic study material will be available in the Learning Management System physically or through the corresponding internet links.


HART, H.; HART, D. J.; CRAINE, L. E., Organic Chemistry: A Short Course. Ed Houghton Mifflin Compay, ISBN 9780618590735

VOLLHARDT, K. P. C.; SHORE, N. E. Organic Chemistry ", Ed W. H. Freeman, ISBN 9781429239240


COMPLEMENTARY BIBLIOGRAPHY

William Reusch, Virtual Textbook of Organic Chemistry (free access under Creative Commons License)

Basic competences:

- CB4 Ability to transmit information, ideas, problems and solutions to an specialized audience as well as to a non-specialized audience

Specific competences - Basic Module:

- FB.4.2 Ability to understand and apply the basic knowledge of organic Chemistry in Engineering.

General competences:

- CG.3 Knowledge in basic topics and technologies. This will allow the students to learn new methods and theories to adapt to new situations.
- CG.4 Ability to solve problems with initiative, to take decisions, creativity, critical reasoning. Ability to communicate and to transmit knowledge and skills related to industrial engineering.
- CG.10 Ability to work in a multilingual and multidisciplinary environment.

Transverse competences:

- CT.1 Ability of analysis and synthesis
- CT.3 Oral and written communication in mother languages and some foreigner
- CT.4 Skills using computer applications
- CT.6 Problem solving
- CT.8 Teamwork
- CT.13 Ability to apply the knowledge in practice
- CT.16 Sensibility towards environmental topics

The subject will have a Learning Management System using the Moodle platform in which the whole teaching material of the course, including the schedule and links to pages of interest, will be provided. The Learning Management System will be the primary communication channel with the students.

Teaching activities are distributed as follows:
• 28 hours for expository classes
• 9 interactive hours of seminar
• 12 hours of laboratory practices
• 3 hours of computer practices
• 2 hours of tutoring

Lecture teaching:
- Theoretical explanations will be alternated with the resolution of exercises to illustrate the explained concepts.

Interactive learning:
- The active participation of the students in answering question and solving problems will be taken into account.

- Tutorial classes. Besides clarifying doubts, complementary problems can be discussed.

- Laboratory classes: three laboratory practices of 4h. In each session 1-2 experiments will be done. A laboratory manual with the fundamentals and the experimental procedures for each experiment will be provided to the students. The attendance to the laboratory practices will be mandatory to pass the course.

- Computer practices: One session class using computer programs to represent organic molecules.

In addition, for practical computer classes, students will be able to download to their personal computer equipment the ChemDraw and Chem3D programs, for which the USC has a Campus license.


Competences:
- Lecture teaching: CB4, CG3, CT1, CT3, CT13, FB4.2
- Seminar classes: CB4, CG4, CG10, CT1, CT3, CT6, CT8, CT13, CT16
- Tutorial classes with small groups of students: CB4, CG4, CT8
- Laboratory classes: CG3, CT1, CT13, CT16, FB4.2
- Computer practices: CT4, CT13, FB4.2
- Learning Management System: CG.10, CT.4,FB.4.2

- FINAL EXAM: with theoretical and practical questions during the period of examinations, at the end of the course. It will contribute 70% to the overall grade. It is necessary to obtain a minimum grade of 4 in the final exam to pass the course.

- CONTINUOUS ASSESSMENT (25%): Execution of exercises in the seminars, active class participation and written controls to be done during class hours (during lectures, seminars, or tutorial classes) that will consist in the resolution of several exercises related to the studied topics.

- LABORATORY AND COMPUTER CLASSES (5%). Attendance is mandatory to pass the subject.

- The pass is achieved with a minimum grade of 5.

The students who fail the subject in the first opportunity of the final exam, will have a second opportunity in July. All the marks obtained in the other components of the grading, continuous assessment and practical work, will be kept.

FRAUDULENT ASSESSMENT OF EVALUATION TESTS
In cases of fraudulent performance of exercises or tests, the provisions of the “Regulations for the assessment of the academic performance and the review of qualifications” will apply: "The fraudulent conduct of any exercise or test required in the assessment of a subject will involve the qualification of fail in the corresponding call, regardless of the disciplinary process that may be followed against the offending student."


Competences:
- Exam: CB4, CG3, CG4,CT1, CT3, CT6, CT13, FB4.2
- Continuous assessment: CB4, CG4, CG10, CT3, CT6, CT8 CT13, CT16
- Work in the laboratory and in the computer class: CG3, CT1, CT4, CT13, CT16, FB4.2
- Tutorships: CB4, CG4, CT8

Activity Work in class (hours) Personal work (hours)
Theoretical classes 28 37
Seminars 9 15
Computer practices 3 2
Laboratory Practices 12 8
Tutorships (groups) 2 3
Tutorships (individual) 2 2
Exam and revision 5 22
Total 61 89

It is important that the students had previously studied the following subjects: Química Fundamental, Fundamentos de Procesos Químicos and Química Inorgánica.
It is highly recommended the attendance to and the active participation in every class.
It is recommended the handle of molecular models
It is very important to keep up to date with the study of the subject and to work on the questions/exercises before they are addressed in class.

There will be two groups: In one group the classes will be in Spanish (Prof. Agustín Cobas Martínez) and in the other one the classes will be in English (Prof. Moisés Gulías Costas)

The students are required to know and follow the rules included in the Protocol of basic safety training for experimental spaces of the School of Engineering, available in the security section of its new website to which you can access as follows:
1. Access your intranet.
2. Enter Documentation / Security / Training.
3. Click on "Basic Safety Training Protocol for Experimental Spaces."