Molecular Basis of marine environmental adaptation

To present the biochemical mechanisms that are behind the specific adaptations that organisms evolved to adapt to the aquatic environment.

Item 1. Biochemical adaptation: basic mechanisms and strategies. Time of biochemical adaptations

Item 2. Design of cellular metabolism. Metabolic adaptation at the level of Glycolysis points. Origin and phylogenetic distribution of the urea cycle. Adaptations in mitochondrial energy metabolism.

Item 3. Adaptation of enzymes to metabolic functions: enzymatic regulation mechanisms. Enzymes as elements of protection.

Item 4. Adaptation to the limited availability of oxygen: anaerobic metabolism of marine invertebrates. Anaerobic metabolism of marine vertebrates. Adaptation to hypoxia.

Item 5. Adaptacion to salinity: osmotic regulation of aquatic organisms. Regulating the response to osmotic shock.

Item 6. Adaptation to temperature: compensatory mechanisms to variations in temperature of poiquilotermos organisms. Temperature acclimation mechanisms. Adaptation to the ice.

Item 7. Adaptation to pressure: effects of hydrostatic pressure on biological systems. Mechanisms of perception and compensation to pressure changes.

Atkinson D.E. , Cellular Energy Metabolism and its Regulation, 1977, Academic Press, Inc.

Di Prisco, G. , Life under extreme conditions, 1991, Springer-Verlag

Ewart K.V., Fish antifreeze proteins. Molecular aspects of fish and marine biology, 2002,

Hochachka, P.W. and Somero G.N., Strategies of Biochemical adaptation, 1973, Int. Thomson Publis

Hochachka, P.W. and Mommsen T.P. , Metabolic Biochemistry, 1995, Elsevier

Hochachka P.W and Somero G.N., Biochemical Adaptation, 2002, Oxford niversity Press

Le Gal, Y. , Biochimie Marine, 1988, Masson, París

Lucas A. , Bioenergetics of Aquatic Animals , 1997 , Taylor & Francis

Mathews-Van Holde, Bioquímica, 2006, McGraw Hill

Nelson D.L and Cox M.M., Lehninger. Principios de Bioquímica, 2015, Ediciones Omega

Salway J., Metabolism at a glance, 2004, Blackwell Publishing Limited.

Urich, K. , Comparative Animal Biochemestry, 1994, Springer-Verlag

Acquisition of basic concepts about the structure of biomolecules, the metabolic reactions, the main processes of obtaining and use of energy and the transmission and expression of genetic information.

Approach of adaptive phenomena in molecular terms.

Knowledge of the basic mechanisms and strategies of adaptation at the molecular level.

Knowledge of main adaptive points of the energy metabolism.

Interpretation of molecular adaptation to the main variable factors of the marine environment.

Acquisition and appropriate use of biochemical concepts and terminology.

Development of the style of scientific thought.

Master session: teacher will give fundamental notions so that students understand and can prepare the contents of the field.

Seminars: students work issues or bibliographic data related to the subject and elaborate reviews or presentations that will defend orally.

Master session: the acquired theoretical knowledge will be assessed through a final test type test. 70% of the final grade

Seminars: the ability to relate knowledge and concepts acquired, the correct use of the terminology of the matter and the critical capacity and synthesis will be valued in the work done in the workshops. 30% of the final grade

------------------------------MASTER SESSION-----SEMINARS----------TEST
STUDENT CLASSROOM ---------20--------------------4-------------------1
HOURS

FACTOR OF WORK---------------2---------------------2.5

STUDENT PERSONNEL ----------40--------- ----------10
WORK HOURS

TOTAL HOURS OF---------------60-------------------14-------------------1
PERSONAL WORK


TOTAL HOURS: 75

ECTS: 3

Master session provides personalized attention during the preparation of the matter to solve the raised doubts and receive the necessary support in the preparation of the seminar through voluntary tutoring.

Seminars provide a personalized attention during the preparation of the matter to solve the raised doubts and receive the necessary support in the preparation of the seminar through voluntary tutoring.

The realization of seminars and bibliographic work is compulsory for the overcoming of the matter. The final test is mandatory for the overcoming of the matter.
Note in each of the parties corresponding to the subject taught by each teacher shall be 3 (out of 10) to make the average. The average exam mark shall be 3.5 (35% of the valuation of the subject), so that is taken into account the valuation of the seminars.