ECTS credits ECTS credits: 3
ECTS Hours Rules/Memories Hours of tutorials: 2 Expository Class: 15 Interactive Classroom: 10 Total: 27
Use languages Spanish, Galician
Type: Ordinary subject Master’s Degree RD 1393/2007 - 822/2021
Departments: Analytical Chemistry, Nutrition and Bromatology
Areas: Analytical Chemistry
Center Faculty of Chemistry
Call: First Semester
Teaching: With teaching
Enrolment: Enrollable | 1st year (Yes)
Situation, meaning and importance of the subject in the field of the degree.
- Specialty to which the subject belongs in the Study Plan. Subjects with which it relates.
The compulsory subject belongs to Module M1 (COMPULSORY ADVANCED CHEMICAL TRAINING) which is shared with 4 other subjects: Materials Characterization Techniques and Biointerphases, Advanced Structural Determination, Industrial Processes and Sustainability, and finally Tutored Training Activities. Module 1 to which this subject belongs is common in the training of students with both a research and professional profile.
It is related to the subjects of the same module and with the electives of the specialty Module M6 (ADVANCED ANALYTICAL TECHNIQUES)
- Role that this course plays in this training block and in the whole Curriculum.
This subject is key in the Advanced Compulsory Training module because it completes the study of Analytical Chemistry taught in the Degree in Chemistry. Its objective is to train the student for the proper selection of the analytical methodology based on its applicability and the selection, calculation and evaluation of the appropriate criteria for the proposed purpose in control laboratories and industry.
- Previous knowledge (recommended / compulsory) that students must possess to take the subject.
Basic knowledge in Analytical Chemistry and Chemical Analysis
- Interest of the subject for the future profession
Provide the student with the necessary knowledge to select the appropriate analytical methodology based on the application and the analytical criteria required for it.
Provide the student with knowledge of the basic principles for good practices in analytical measurement, emphasizing the importance of using validated methods.
Provide the student with the necessary information on the validation of analytical methods in accordance with official guidelines, as well as the analytical criteria that must be evaluated to ensure the proper functioning and applicability of said method.
To develop in the student their ability to solve real problems of practical analysis cases of interest in different areas (food, environmental, clinical, etc.).
Introduce the student to innovative techniques of analysis, of interest in the industrial and research fields
Learning outcomes and skills to be achieved by the student with the subject.
- Learning outcomes.
At the end of the study of this subject, the student must have acquired knowledge about the adequate selection of the analytical methodology based on the proposed purpose, as well as how to implement and be able to apply and evaluate the operating criteria of the method in order to know how to validate said method. in accordance with officially established guidelines. On the other hand, innovative techniques will be addressed both in the treatment of the analytical sample, as well as in the determination techniques and data treatment procedures. Finally, the knowledge acquired will be applied in solving practical cases of interest in various fields of analysis (food, clinical, environmental, etc.). Also, examples of innovative techniques can be shown both in the treatment of the analytical sample, as well as in the determination and treatment of data.
Contents of the subject.
- Descriptors of the subject:
Selection of analytical methodologies. Implementation, selection of criteria for the operation of a method and their evaluation. Validation of an analytical method: Official guidelines. Case studies. Innovative Technologies in Analytical Chemistry.
- Subject headings:
Expository classes program
Topic 1. Introduction: Selection of analytical methodologies
Selection criteria for an analysis method. Classification of methods of analysis. Qualitative and quantitative analysis characteristics
Topic 2. Validation of analytical methodologies
Selection of performance criteria for a method. Development, evaluation and use of an analytical methodology. Official guidelines for the validation of an analytical method. Validation tools. Types of intra or interlaboratory validation. Evaluation of validation studies
Topic 3 Study of practical cases
Innovative Technologies in Analytical Chemistry. Automation and miniaturization in Analytical Chemistry
Seminary class program
Acquire a comprehensive knowledge of data analysis making use of programs available to USC students and others and computer resources. The knowledge acquired can have important applications in the students' scientific research methodology in their professional future. Practical examples will be addressed in which it is learned to determine with statistical basis the optimal operational conditions of a process, that a method is adequate for the intended purposes, ensure that the results obtained through a methodology are reliable and of quality:
1. Analytical process optimization study
2. Application of validation tools
3. Evaluation of the matrix effect in different analytical methods
4. Example of validation of an analytical method I
5. Example of validation of an analytical method II
6. Application of innovative analytical techniques to real analytical problems
7. Design of schemes of automatic / miniaturized procedures
Basic (reference manuals).
R. Kellner, J. M. Mermet, M. Otto, M. Valcarcel y H. M. Widmer, Eds. “Analytical Chemistry: A Modern Approach to Analytical Science“.Ed. Wiley-VCH. 2004.
Eurolab España. P.P. Morillas y colaboradores. Guía Eurachem: La adecuación al uso de los métodos analíticos – Una Guía de laboratorio para la validación de métodos y temas relacionados (1ª ed. 2016). Disponible en www.eurachem.org
M. VALCARCEL. "Principios de Química Analítica". Springer, Barcelona (1999).
Complementary.
Ramis Ramos G., García Álvarez-Coque M.C. “Quimiometría “. Síntesis. Madrid. 2001.
Compañó Beltrán R., Rios Castro A. “Garantía de calidad en los laboratorios analíticos”. Síntesis. Madrid. 2002
Valcárcel M., Cárdenas M.S. “Automatización y Miniaturización en Química Analítica“.Ed. Springer. 2000.
Validación de Métodos Analíticos Cualitativos. I. Rodríguez, E. Trullos, X. Rius Técnicas de Laboratorio, 281 (2003) 328-335. http:/www.quimica.urv.es/quimio
Kruve A. et al. Tutorial review on validation of liquid chromatography–mass spectrometry methods: Part I Analytica Chimica Acta 870 (2015) 29–44
Kruve A. et al. Tutorial review on validation of liquid chromatography–mass spectrometry methods: Part II Analytica Chimica Acta 870 (2015) 8–28
Use of Statistics to develop and evaluate Analytical methods. Grant T. Wernimont Edited by William Spendle. AOAC International 1985
AOAC and IUPAC Official Guidelines for Validation of Analytical methods 2016
Basic and general skills
CG5 - Use scientific terminology in English to argue the experimental results in the context of the
chemical profession
CG6 - Correctly apply the new technologies for the collection and organization of information to solve problems in the
professional activity
CG8 - Assess the human, economic, legal and technical dimension in professional practice, as well as the impact of chemistry on the
environment and in the sustainable development of society.
CB7 - That students know how to apply the knowledge acquired and their ability to solve problems in environments
new or little known within broader (or multidisciplinary) contexts related to your area of study
CB8 - That students are able to integrate knowledge and face the complexity of formulating judgments based on
information that, being incomplete or limited, includes reflections on the social and ethical responsibilities linked to the
application of your knowledge and judgment
CB10 - That students possess the learning skills that allow them to continue studying in a way that will be largely self-directed or autonomous.
Transversal competences
CT1 - Prepare, write and publicly defend scientific and technical reports.
CT2 - Work in a team and adapt to multidisciplinary teams.
CT3 - Work autonomously and efficiently in the daily practice of research or professional activity.
CT4 - Appreciate the value of quality and continuous improvement, acting with rigor, responsibility and professional ethics.
Specific competences
CE4 - Innovate in chemical synthesis and analysis methods related to the different areas of Chemistry
CE5 - Correctly assess the risks and the environmental and socioeconomic impact associated with special chemical substances
CE6 - Design processes that involve the treatment or elimination of hazardous chemicals
CE7 - Operate with advanced instrumentation for chemical analysis and structural determination
CE8 - Analyze and use the data obtained autonomously in complex laboratory experiments by relating them
with the appropriate chemical, physical or biological techniques, and including the use of primary bibliographic sources
TEACHING METHODOLOGIES
Face-to-face lectures (use of a blackboard, computer, cannon), complemented with the tools of virtual teaching.
Face-to-face seminars conducted with the Master's own teaching staff. Interactive sessions related to the different subjects with debates and exchange of opinions with the students. Practical examples will be carried out in the computer room.
Resolution of practical exercises (problems, multiple choice questions, interpretation and processing of information, evaluation of scientific publications, etc.)
Individual or small group tutorials that may be partially carried out electronically.
Carrying out work, both individually and in groups, on scientific topics related to the different subjects of the Master.
Oral presentation of works, reports, etc., including debate with teachers and students.
Use of specialized computer programs and the internet. Online teaching support (Virtual Campus).
Experimental work on basic laboratory work techniques
Personal study based on the different sources of information
Completion of the different tests to verify the obtaining of both theoretical and practical knowledge and the acquisition of skills and attitudes
Stay in the laboratory or in a company to carry out advanced practices and / or the final master's project. Individual practical work under the supervision of a personal tutor, with the adequate infrastructure and other necessary means to be able to achieve the proposed objectives
General considerations
Scenario 1: adapted normality.
The evaluation of this subject will be done by means of continuous evaluation and the realization of a face-to-face final exam, the access to the exam being conditioned to participation in at least 80% of the face-to-face teaching activities of compulsory attendance (lectures, seminars / practices and tutorials ).
The continuous assessment (L1) will have a weight of 40% in the grade of the subject and will consist of two components: interactive classes in a small group (seminars) and interactive classes in a very small group (tutorials). The seminars and tutorials will include the following elements: problem solving and practical cases, oral presentation (works, reports, problems and practical cases), attendance and participation and continuous evaluation of the student through questions and oral questions during the course (40%) .
The final exam (N2) will deal with all the contents of the subject.
The student's grade will be obtained as a result of applying the following formula:
Final grade = 0.4 x N1 + 0.6 x N2
N1 being the numerical mark corresponding to the continuous assessment (0-10 scale) and N2 the numerical mark of the final exam (0-10 scale).
Repeating students will have the same class attendance regime as those taking the subject for the first time.
In cases of fraudulent performance of exercises or tests, the provisions of the Regulations for the evaluation of the academic performance of students and the review of qualifications will apply.
Evaluation criteria
ASSESSMENT SYSTEM WEIGHTING ASSESSED COMPETENCES
Final exam 60 CG5, CB7, CE8, CG6, CG8, CB10, CE5, CE6
Troubleshooting and case studies 10 CB8, CT1, CT2, CT3, CE4, CE7, CE8
Oral presentation
(works, reports, problems and practical cases) 10 CG5, CT1
Attendance and participation 10 CB10, CT3, CE7
Continuous evaluation of the student
(through questions and oral questions during the course 10 CB8, CT2, CT4, CE5, CE6, CE7
TRAINING ACTIVITY HOURS PRESENTIALITY
Theoretical face-to-face classes 15 100
Seminars 5 100
Scheduled tutorials 6 100
Test preparation and supervised work 20 0
Student's personal study 37 0
Experimental work in the laboratory 10 100
Students must review the theoretical concepts introduced in the different topics using the recommended bibliography and summaries. Those students who encounter significant difficulties when working on the proposed activities, should establish, in agreement with the teachers, the face-to-face and / or online tutoring sessions, with the aim that they can analyze the problem and help to solve these difficulties.
Maria Del Carmen Yebra Biurrun
- Department
- Analytical Chemistry, Nutrition and Bromatology
- Area
- Analytical Chemistry
- Phone
- 881814267
- mcarmen.yebra [at] usc.es
- Category
- Professor: University Professor
Antonia María Carro Díaz
Coordinador/a- Department
- Analytical Chemistry, Nutrition and Bromatology
- Area
- Analytical Chemistry
- Phone
- 881814388
- tuchi.carro [at] usc.es
- Category
- Professor: University Professor
| Monday | |||
|---|---|---|---|
| 16:00-18:00 | Grupo /CLE_01 | Spanish | Inorganic Chemistry Classroom (1st floor) |
| Friday | |||
| 16:00-18:00 | Grupo /CLE_01 | Spanish | Inorganic Chemistry Classroom (1st floor) |
| 01.08.2025 10:00-14:00 | Grupo /CLE_01 | Inorganic Chemistry Classroom (1st floor) |