ECTS credits ECTS credits: 4.5
ECTS Hours Rules/Memories Student's work ECTS: 74.25 Hours of tutorials: 2.25 Expository Class: 18 Interactive Classroom: 18 Total: 112.5
Use languages Spanish, Galician, English
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Organic Chemistry
Areas: Organic Chemistry
Center Faculty of Chemistry
Call: Second Semester
Teaching: Sin Docencia (En Extinción)
Enrolment: No Matriculable (Sólo Planes en Extinción)
Propose strategies to solve problems related to synthetic organic chemistry, using models previously developed to solve them.
Learning the fundamental concepts for the synthesis of organic molecules, including:
- Functional group interconversion
- Main reactions for carbon-carbon bond formation
- The use of protecting groups
- Retrosynthetic analysis
THEORETICAL PART OF THE COURSE
UNIT 1: INTRODUCTION.
UNIT 2: REACTIONS OF OXIDATION AND REDUCTION
UNIT 3: FORMATION OF SIMPLE CARBON-CARBON AND CARBON-HETEROATOM BONDS.
UNIT 4: FORMATION OF DOUBLE CARBON-CARBON BONDS.
UNIT 5: PERICYCLIC REACTIONS.
UNIT 6: ORGANIC SYNTHESIS: RETROSYNTHETIC ANALYSIS AND PROTECTING GROUPS.
EXPERIMENTAL PART OF THE COURSE
Three practical work sessions of 4 hour each throughout the second quarter.
Contents: Synthesis and purification of 3,3-dimethylcyclohexanone by means of 1,4-addition of lithium dimethylcuprate to 3-methylcyclohex-2-en-1-one. This experiment will involve the use of reagents under an inert atmosphere and low temperature.
LITERATURE.
BASIC: Organic Chemistry (Clayden Greeves, Warren and Wothers. Oxford. University Press. ISBN: 978-0-19-850346-0). Análisis Retrosintético y Síntesis Orgánica (Miguel Carda, Alberto Marco, Juan Murga, Eva Falomir. Universitat Jaume I. www.tenda.uji.es. ISBN: 978-84-8021-759-0). Síntesis Totales (Miguel Carda, Eva Falomir. Universitat Jaume I. www.tenda.uji.es. ISBN: 978-84-8021-684-5)
ADVANCED: Name Reactions for Functional Group Transformations (J. J. Li, E. J. Corey. John Wiley and Sons, Pub. ISBN: 978-0-471-74868-7. L. Kürti, B. Czakó. Strategic Applications of Named Reactions in Organic Synthesis. Elsevier. ISBN-13: 978-0-12-429785-2. I. Ojima. Catalytic Asymmetric Synthesis. Wiley. ISBN: 0-471-29805-0. K. Mikami, M. Lautens. New Frontiers in Asymmetric Catalysis. Wiley. ISBN: 978-0-471-68026-0, Advanced Organic Chemistry, F.J. Carey and R.J. Sundberg. Springer. ISBN 978-0-387-44899-2.
BASIC AND GENERAL
CG2 - To be able to gather and interpret data, information and relevant results, to draw conclusions and to issue reasoned reports on scientific, technological or other areas requiring the use of chemical knowledge.
CG3 - To apply both theoretical and practical acquired knowledge, and the ability of analysis and abstraction in the definition and approach to problems, finding solutions in both academic and professional contexts.
CG4 - To have the ability to communicate, both in writing and orally, knowledge, procedures, results and ideas in Chemistry both to specialist and non-specialist public.
CG5 - To be able to study and learn independently, by organizing time, resources, new knowledge and techniques in any scientific or technological discipline.
CG1 - To understand concepts, methods and main results in Chemistry, with a historical perspective of their development.
CB1 - To demonstrate knowledge and understanding in a field of study that is typically at a level which, although it is supported by advanced textbooks, includes some aspects involving knowledge of the forefront of their field of study
CROSS
CT1 - To acquire skills for analysis and synthesis.
CT2 - To develop capacity for organization and planning.
CT3 - To acquire knowledge on a foreign language.
CT4 - To be able to solve problems.
CT5 - To be able to make decisions.
SPECIFIC
CE4 - To know the main types of chemical reactions.
CE14 - To be able to solve qualitative and quantitative problems according to previously developed models.
CE15 - To be able to recognize and to analyze new problems and to plan strategies to solve them.
CE18 - To be able to perform laboratory procedures involved in standards analytical and synthetic work in conjunction with organic and inorganic systems.
CE22 - To understand the relationship between theory and experiments
The matter have a virtual classroom where students will find all the information and materials relating to the subject: teaching guide, presentations, exercises, notices, etc.
The training classroom activities consist of:
A) Lectures in large group:
Lessons taught by the professor who may have different formats (theory, problems and / or general examples ...). The professor may have the support of audiovisual and computer media. In addition molecular models will be handled and students use is recommended.
B) Interactive classes in small group (seminars):
Theoretical / practical lessons in which applications of theory, problems, exercises ... are solved. The student participates actively by delivering exercises to the teacher (problem sets given to the students in advance) and solving exercises in the classroom. The use of molecular models is recommended. Attendance at these classes is mandatory.
C) Laboratory practical classes:
Practical classes that take place in the laboratory. The student acquires skills on a chemistry lab and consolidates the knowledge acquired in the theory classes. For these practices, the student will have a laboratory manual, which will include general considerations on laboratory work and the guidelines for each lab session, including the methodology to follow, the calculations to be performed and the results to be presented. The student has to attend every practice session having read carefully the contents of this manual. After an explanation of the teacher, the students will work individually or in pairs. Delivery of the laboratory notebook is an additional requirement for evaluation. Attendance at these classes is mandatory. Absences must be justified by appropriate documents.
D) Tutorials in very small group:
Two tutorial sessions are scheduled by the professor and coordinated by the Center, in order to clarify doubts about the theory or practice. Problems, exercises, or other tasks will be proposed in small groups. Attendance at these classes is mandatory.
The general evaluation criterion of the Degree in Chemistry will be followed.
1. There will be one single call
2. Two final exams/opportunities for each call (first in May/June, second in July)
3. Attendance to 80% of seminars/laboratory/tutorials is mandatory. The laboratory practices must be carried out in their entirety and those not carried out must be recovered in agreement with the teacher and within the scheduled time for the subject. Absences must be duly justified.
4. The evaluation of the subject will be done through continuous evaluation and the completion of a final exam. The evaluation will consist of two parts:
a. Continuous evaluation, which may in turn include:
i. Exercises given to the teacher (Ej_entr)
ii. Exercises carried out in the seminars (Ej_sem)
iii. Work in tutorials (Tut)
iv. Laboratory practices (Pract)
b. Final exam (EF)
5. To pass the course, it is necessary to obtain the grade of PASS in the laboratory practices (continuous assessment grade), for which the student must carry out all the practices, recovering them in case of duly justified absences, according to the teacher .
6. The student's grade, which will not be lower than the final exam or the one obtained by weighing it with the grade of the continuous assessment, will be obtained as a result of applying the following formula:
Final note = maximum (c1 x N1 + c2 x N2, N2)
Being N1 the numerical score corresponding to the continuous evaluation (scale 0-10), N2 the numerical grade of the final exam (scale 0-10), c1 the percentage weight of the continuous assessment (30% = 0.3), c2 the percentage weight of the exam grade (1-c1, 70% = 0.7).
7. Each subsection of section 2.1 will count towards the final grade of the student as follows:
a (i, ii, iii). fifteen%
b (iv). Pract 15%
c. EF 70%
8. For the evaluation of laboratory practices, the evaluated items will be the following: organization, neatness in the laboratory, observation of safety standards, understanding and execution of the practice and laboratory notebook.
9. The final exam will deal with assumptions related to the theoretical aspects of the subject and may also include a second part in which issues related to laboratory practices will be raised. The practical contents-laboratory will have a percentage weight of 10% on the final grade of this exam.
10. Students enrolled in a theoretical-practical subject who have already passed the laboratory practices, will retain this qualification for a maximum of two academic years, not having to do the practices again. They must, therefore, attend only 80% of the remaining interactive classes.
11. Evaluation of Competences:
SEMINARS: CB1, CG1, CG2, CG3, CG4, CT3, CT4, CE4, CE14, CE15
TUTORIALS: CG2, CG3, CG4, CT4, CE4, CE14, CE15
PRACTICAL CLASSES: CG2, CG3, CT1, CT2, CT5, CE4, CE15, CE18, CE22
EXAM: CB1, CG1, CG3, CG5, CT1, CT2, CE4, CE22
12. In cases of fraudulent performance of exercises or tests, the provisions of the "Regulations for the evaluation of the academic performance of students and the review of grades" will apply.
The number of ECTS credits of the subject is 4.5 (3.5 theoretical/practical + 1 laboratory credits), corresponding to 112.5 total hours of student work, distributed according to the following table:
Classroom/laboratory
Lectures in large group, 18 h
Interactive clases in small group (seminars), 8 h
Interactive clases in very small group (tutorials) 2 h
Laboratory Practice 12 h
Personal work
Individual self-study or in group, 36 h
Exercises 16 h
Preparation of written and oral presentations and activities in library or similar 12.5 h
Preparation of laboratory work and reporting, 8 h
Total working hours in the classroom or laboratory 40 h
Total hours of personal work 72.5 h
As a prerequisite to Organic Chemistry IV, it is mandatory to have completed Organic Chemistry I, II, III and Structural Analysis
- It is advisable to attend lectures.
- It is important to work on the matter every day.
- The resolution of exercises is essential for learning this subject.
- For exercises involving concepts of stereochemistry it is advisable to use molecular models.
- It is essential the preparation of the practices before entering the laboratory.
EVALUATION SYSTEM
In cases of fraudulent performance of exercises or tests, the provisions of the “Regulations for evaluating student academic performance and reviewing grades” will apply.
Juan Ramón Granja Guillán
Coordinador/a- Department
- Organic Chemistry
- Area
- Organic Chemistry
- juanr.granja [at] usc.es
- Category
- Professor: University Professor
Jose Luis Mascareñas Cid
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- Phone
- 881815737
- joseluis.mascarenas [at] usc.es
- Category
- Professor: University Professor
Francisco Javier Sardina Lopez
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- Phone
- 881815715
- javier.sardina [at] usc.es
- Category
- Professor: University Professor
Moises Gulias Costa
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- Phone
- 881815790
- moises.gulias [at] usc.es
- Category
- Professor: University Lecturer
Axel Sarmiento Fuentes
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- axel.sarmiento.fuentes [at] usc.es
- Category
- Ministry Pre-doctoral Contract
Lucia Gomez Rodrigo
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- luciagomez.rodrigo [at] usc.es
- Category
- USC Pre-doctoral Contract
Ivan Huertas Morales
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- ivan.huertas.morales [at] usc.es
- Category
- Ministry Pre-doctoral Contract
Kaddy Saho
- Department
- Organic Chemistry
- Area
- Organic Chemistry
- ka.saho [at] usc.es
- Category
- Ministry Pre-doctoral Contract
| Tuesday | |||
|---|---|---|---|
| 13:00-14:00 | Grupo /CLE_03 | English | Classroom 3.44 |
| 13:00-14:00 | Grupo /CLE_02 | Spanish | Inorganic Chemistry Classroom (1st floor) |
| Wednesday | |||
| 11:00-12:00 | Grupo /CLE_01 | Spanish | Organic Chemistry Classroom (1st floor) |
| Thursday | |||
| 09:00-10:00 | Grupo /CLE_01 | Spanish | Organic Chemistry Classroom (1st floor) |
| 13:00-14:00 | Grupo /CLE_03 | English | Classroom 3.44 |
| 13:00-14:00 | Grupo /CLE_02 | Spanish | Inorganic Chemistry Classroom (1st floor) |
| 06.02.2025 10:00-14:00 | Grupo /CLE_01 | Biology Classroom (3rd floor) |
| 06.02.2025 10:00-14:00 | Grupo /CLE_01 | Mathematics Classroom (3rd floor) |
| 06.20.2025 10:00-14:00 | Grupo /CLE_01 | Inorganic Chemistry Classroom (1st floor) |
| 06.20.2025 10:00-14:00 | Grupo /CLE_01 | Organic Chemistry Classroom (1st floor) |